Research Groups within Organic Chemistry
Functional Molecular Entities - Organic synthesis of functional entities: Supramolecular host-guest systems, photoswitchable peptidomimetics, and monomers for conducting redox polymers. Our main tools are organometallic synthesis, peptide synthesis, and NMR spectroscopy.
Targeting Hypoxia in Cancer Therapy and Diagnosis - Organic synthesis of luminescent heterocyclic compounds, target-specific imaging agents, and hypoxia-activated prodrugs.
Graphene from a Molecular Perspective - Purification, derivatisation and evaluations of fullerenes and carbon nanotubes; synthesis and chemical functionalization of graphene. Dyes and dyads for electron transfer studies, solar cells and molecular electronics applications. Supramolecular & organometallic chemistry.
Chemical Tools for Research and Drug Discovery Beyond Traditional Drug Space - Chemical probes for difficult targets that conquer complex disease.
Synthetic Methodology, Catalysis and Green Chemistry - The group pursues the development of faster, cheaper and greener organic transformations using C-H activation, arynes and mechanochemistry.
Halogen Bonding, NMR Method Development, Antibiotic Resistance and Natural Product Chemistry - Halogen bonding, antimalarial natural products from plants in East Africa, paramagnetic ligand tagging technology and development of Metallo-Beta-Lactamase inhibitors to control antibiotic resistance.
Quantum Chemistry - Electronic structure and dynamics simulations, and modelling of electronic structure theory plays a central role in our research projects. Current applications include simulations of properties of chemiluminescent molecules, photochemistry, and interpretation of spectra. Developments are focused on multi-configurational wave function theoryand their implementations in the software package OpenMolcas.