Ongoing research within Computational Biochemistry in Lynn Kamerlin Group

Our group has broad research interests, that focus on applying the tools of computational (bio)chemistry to understanding the chemical basis for complex biological problems. This spans a range of problems from understanding fundamental chemical reactivity through to understanding the physicochemical parameters that allow for the evolution of new enzyme functions. Current projects in the research group include studying the role of ligand-gated conformational changes in enzyme catalysis, protein-DNA recognition, DNA proofreading and repair, enzyme evolution, GTPase regulation, the dynamical behavior of disordered peptides, as well as the development of new approaches for computational enzymology.

For further information, please see our publication list.

To see our partners, please visit our funding page.